Month: May 2022

$4.5 Million in Grant Funding Expands New Alzheimer’s Early Detection and Healthcare System Preparedness Efforts

GENEVA, SWITZERLAND, May 23, 2022 (GLOBE NEWSWIRE) — The Davos Alzheimer’s Collaborative (DAC), the organization leading an unprecedented global response to Alzheimer’s disease, today announced the recipients of a grant program aiming for early detection of cognitive symptoms. The early detection grants total $4.5 Million from 8 countries across North America, Europe, Asia, and Africa.

The grants are an initiative of the DAC Healthcare System Preparedness Project, which aims to advance how healthcare systems worldwide detect, diagnose, treat, and care for people with or at risk for Alzheimer’s.

Grantees are located throughout the US, Brunei, Kenya, Germany, Japan, Canada, Cuba, and Armenia. Several grants will focus on expanding cognition screening and training for primary care providers. Others are harnessing innovative technologies to utilize optometrists and pharmacists. This will expand the pool of frontline workers available to screen for early detection, and reduce the unnecessary use of  specialist care. Another deploys a mobile clinic to offer direct clinical support or equip digital tablets to volunteer workers to rapidly improve detection  rates.

According to George Vradenburg, Founding Chairman of the Board, Davos Alzheimer’s Collaborative, “Each grant will bring unique and measurable benefits to its local health system and community and, through DAC’s global learning network, will also spread their learnings broadly around the world. Finding new and innovative ways to advance early detection is paramount to improving healthcare systems’ abilities to provide better care today, and to prepare for the future availability of treatments.”

The grant application process was extensive, with DAC receiving 76 responses from 21 countries in two months. A diverse panel of experts, including a family member of an Alzheimer’s patient living with the disease, served as an independent review committee for these grants:

• Tarun Dua (Global) – World Health Organization
• Wendy Weidner (Global) – Alzheimer’s Disease International
• Ricardo Allegri (Argentina) – University of Buenos Aires & World Dementia Council
• Chirine Chehab (Lebanon) – American University Hospital of Beirut
• Lori Frank (United States) – RAND Corporation & New York Academy of Medicines
• Ryoji Noritake (Japan) – Health and Global Policy Institute
• Terry Fulmer (United States) – John A. Hartford Foundation
• Chandresh Harjivan (Canada) – Family member of an Alzheimer’s patient

“Early detection of cognitive decline is critical for patients and families and I am excited to see the Davos Alzheimer’s Collaborative tackling this challenge with their Health System Preparedness Initiative,” says Chandresh Harjivan, a family member of an Alzheimer’s patient. “I was honored to be asked to be part of such an esteemed review committee and am very happy that families living with the disease were part of the evaluation process.”

A summary of each grant can be found below. 

About the Davos Alzheimer’s Collaborative

Launched at the World Economic Forum’s 2021 meeting on The Davos Agenda, The Davos Alzheimer’s Collaborative is a multi-stakeholder partnership committed to aligning stakeholders with a new vision for our collective global response against the challenges Alzheimer’s presents to patients, caregivers and healthcare infrastructures. Convened by The World Economic Forum and The Global CEO Initiative on Alzheimer’s Disease (CEOi) and fueled by a mission of service to the estimated 150 million families and half a billion people inevitably impacted by this disease by 2050, DAC is a collaborative for the benefit of all people, in all places.

About DAC’s Healthcare System Preparedness Project

DAC’s Healthcare System Preparedness Project (DAC-SP) is funding innovative approaches that measurably increase rates of cognitive screening, early detection and accurate diagnosis of Alzheimer’s through pilot projects and early detection grants. The pilot projects are: AdventHealth Central Florida, FL, USA; Municipality of Volta Redonda, State of Rio de Janeiro, Brazil; Alzheimer Scotland; University of the West Indies (UWI), Caribbean Institute for Health Research, Jamaica; Kobe University, Japan; INGER/National Institute of Geriatrics, Mexico; and, Indiana University School of Medicine/Indiana University Health, IN, USA. These initiatives are incorporated into DAC Learning Labs, a network of governments and public health and healthcare system leaders, to share best practices that can be scaled globally.

***PLEASE NOTE: Click here to view a recorded discussion with some of the grant recipients, in which over 500 global leaders from 53 countries tuned in to learn about early detection. Click here to be kept informed about updated information regarding the DAC initiative.

Davos Alzheimer’s Collaborative Early Detection Grants

Toronto Memory Program and RetiSpec (Canada)

This project implements the world’s first screening model that leverages collaboration between optometry and a local Alzheimer Society chapter to enable accessible identification of individuals at risk for Alzheimer’s disease and referral to a qualified clinician, facilitating a faster diagnosis. The two community-based entry points include: (1) optometry clinics, where individuals can receive a non-invasive RetiSpec retinal scan for early detection of Alzheimer’s disease; and (2) the Alzheimer Society of Toronto, where individuals can undergo cognitive assessment.

Ludwig-Maximillans University (Germany)       

Partners with two Universities, a health and social care charity, and three industry partners to conduct three screening types on seniors in Germany. This study will identify the best screening method by offering digital cognitive assessments, SCD questionnaire screening, and blood AD biomarkers testing to different groups. This study will also generate a patient registry to enroll patients in the global cohort and clinical trials workstreams, establish a fluid biobank, and train Artificial Intelligence diagnostic systems to better analyze speech patterns.

University of Havana (Cuba)

Provides a two-month training to primary care providers to integrate tablet based cognitive assessments Brain Health Assessment (BHA). The care provider will be assisted by informants, meaning a family-member or other person close to the patient, to help primary care providers determine if a dementia diagnosis is warranted.

Avant Institute (US – Multiple States)

This project implements Cognivue Clarity, a self-administered 10-minute cognitive performance screening tool, to increase access to digital cognitive screening assessments in 20-30 Community Pharmacy Enhanced Services Network (CPESN) pharmacy sites across rural, urban, and underserved communities throughout the United States. This project provides training and onboarding for pharmacies to use Cognivue to screen patients and evaluate the results to make further recommendations and referrals.

Africa Mental Health Research and Training Foundation (Kenya)

This project redeploys existing volunteer staff in the Strengthening Responses to Dementia in Developing Countries (STRiDE) project and trains community health workers to screen 2,400 people aged 60 and above. Workers are equipped with tablets to conduct the screening Instrument for Dementia (CSI-D) cognitive assessment and informant interview, word list recall task, and Euro-Dementia scale. Ultimately, results will inform health system policy and practices in Kenya. 

Alzheimer’s Care Armenia (Armenia)

This cognitive screening education programs utilizes a van that has been outfitted as a multidisciplinary mobile clinic to offer educational programs and work with local clinical staff to screen for cognitive issues using the Montreal Cognitive Assessment (MOCA). The program provides citizens who test positive for cognitive decline with healthcare resources and offers workshops to caregivers on providing support. 

Advocate Aurora Health (US- Illinois)

This project aims to educate primary care providers on the importance of early cognitive screening and provide them with EPIC electronic health record-based digital testing tools to manage their patients efficiently. Clinicians get access to continuing education programming, eConsult support services, and participate in a monthly Project ECHO-type case conference to discuss topics on dementia.

Kobe City Pharmaceutical Association (Japan)   

This project evaluates the value of pharmacy-based digital cognitive tests. It combines the cognitive test with a regular healthcare consultation to increase regular cognitive testing, the rate of early detection of cognitive decline, and timely and accurate diagnosis of dementia in local community-based healthcare system.

University of Washington (US- Washington)     

This project expands the pilot site success of the Gerontological Society of America (GSA) Kickstart, Assess, Evaluate and Refer (KAER Toolkit, 2020 Edition) into a fully operational Cognition in Primary Care (CPC) protocol in seven new primary care clinics across the University of Washington. The CPC model includes provider education training and incorporates two validated tests, the Montreal Cognitive Assessment (MoCa) and the Ascertain Dementia 8-Item Informant Questionnaire (AD8), and a structured Cognitive Checklist. This model checks for comorbidities of dementia and provides guidance on follow-up counseling and referrals to community resources. 

Demensia (Brunei)

This project will perform a pilot test of community screening and information in Senior Citizen Activity Centers, followed by a focus group discussion to select an initial paper-based cognitive assessment. The project will systematically involve communities at grassroots levels – senior citizen activity centres, engagement of village heads and community centres, targeting older people and those with dementia risk factors. Community links formed by the association are available for multisectoral support with this initiative. Other project activities also include training of field workers regarding community screening and cognitive assessment and training workshops for primary care (followed by relevant specialties).

American Academy of Physician Associates and Cleveland Clinic (US – Ohio)

Through partnership with The American Academy of Physician Assistants (AAPA), the Physician Associate (PA) Foundation, and Cleveland Clinic, this project develops cognitive assessment toolkit for non-specialist medical practitioners to be trained in administering screenings, interpreting results, communicating those results and offering additional provider and patient resources. The pilot implementation will be followed by outcomes reporting and dissemination of the toolkit to the network of PA schools and all Cleveland Clinic locations.

Institute for Healthcare Improvement (IHI) (US – Massachusetts)

This project uses a systems redesign approach, working with approximately eight teams across a range of settings on testing and measuring the results of intervention strategies that increase assessment rates. IHI will build and operate a learning community to encourage peer learning among participating teams, provide guidance, and teach scientific improvement methods to facilitate the teams’ testing. Project outputs include a prototype set of interventions, implementation guidance, and an associated measurement set that will be ready to share and scale more widely.

Susan Oliver
Davos Alzheimer's Collaborative
+17032164078
soliver@davosalzheimerscollaborative.org

The CT45x showcases the advantages of TMR sensors to rethink and simplify solutions in the high precision, high current application space

MILPITAS, Calif., May 23, 2022 (GLOBE NEWSWIRE) — Crocus Technology Inc., the leading supplier of disruptive TMR (Tunnel Magneto-Resistance) XtremeSense® sensors, today announced the CT45x family of contactless isolated current sensors to enable high precision and high current measurements in a more simplified solution. Unlike existing solutions, the CT45x allows manufacturers to eliminate costly shields, concentrators or cores. The CT452 and CT453 offers contactless 0.7% accuracy, 1 MHz bandwidth, and better than -50 dB immunity to external magnetic fields without additional mechanical components. This combination of performance and accuracy enables customers to reduce their overall product size and weight which enables them to replace large and costly current sense modules with a small and simple solution.

As current requirements have been increasing so have the challenges of accurately measuring high currents, typically >200 A and often up to 2,000 A. Shunt resistors with isolated amplifiers are broadly used but present an issue with I²R losses and tend to be large and costly. Existing magnetic based solutions like Hall Effect and AMR are less accurate and have high temperature drift. The CT45x products are based on XtremeSense TMR technology that delivers the future with a high signal-to-noise ratio (SNR) contactless approach which can scale with the system requirements, high bandwidth and fast response time, common-model field rejection, combined with high accuracy measurements over temperature.

In addition, many applications now require very accurate current measurements in the milliamp range up to the 1,000 A range or more. Often this type of solution involves multiple current sensors to achieve the desired system performance with many design compromises and complexities. Using Crocus’ XtremeSense TMR current sensors allows for a no-compromise and simple solution using a single CT45x sensor which provides a large dynamic range and a high SNR. For example, the CT45x is able to measure down to 500 mA resolution and up to 1,800 A while maintaining better than 0.7% accuracy.

The CT45x offers groundbreaking noise performance, as low as 0.55 mV_RMS, to enable applications to sense small current levels and small changes or variations in current through a busbar. This performance is almost 10 times better than existing Hall Effect solutions. This results in a SNR (signal-to-noise ratio) as high as 77 dB for the CT45x measurement which allows the system to process higher resolution data with higher accuracy.

“With the introduction of the CT45x family of contactless current sense products, we now have a complete portfolio of products for our customers from small currents to larger currents,” states Zack Deiri, President and CEO of Crocus Technology. “This product based on Crocus’ cutting-edge TMR technology is the most exciting for us as the benefits of our XtremeSense TMR are addressing the needs of higher current applications that can’t be met with existing solutions without compromises. Crocus is excited to be addressing new high current markets such as BMS, Inverters, DC/DC Converter and many others.”

Product features and performance:

CT450 & CT452 (5 V version) & CT453 (3.3 V version)

Isolated Contactless Current Sensor

Capable of measuring currents from 5 mA to >2,000 A

Total output error ±0.7% Full-Scale

300 ns response time, 1 MHz bandwidth

Available in six different configured field ranges

Protection capability with Over Field Detection (OFD)

Integrated Common Mode Field Rejection (CMFR) with >90% immunity (CT452/3)

Uniform magnetic field sensing (CT450)

Targeting applications in EV Chargers, Battery Management Systems (BMS), DC/DC Converters, 48-V system, Bidirectional Charging and AC/DC Inverters.

The CT450 is available in TSSOP-8 package. The CT452/3 are available in TSSOP-16 package For more information, please visit the product webpage:

CT450 https://crocus-technology.com/products/ct450/

CT452 https://crocus-technology.com/products/ct452/

CT453 https://crocus-technology.com/products/ct453/

About Crocus Technology

Crocus Technology develops and manufactures state-of-the-art magnetic sensors based on its patented XtremeSense® TMR sensor technology. Crocus’ disruptive magnetic sensor technology enables the highest sensitivity, the lowest power consumption and smallest size over a wide temperature range. Crocus is headquartered in Milpitas, California. For more information, please visit http://www.crocus-technology.com.

For more information, please contact:

Crocus Technology
Email: info@crocus-technology.com

Le CT45x met en valeur les avantages des capteurs TMR pour repenser et simplifier les solutions dans l’espace des applications de haute précision à courant élevé

MILPITAS, Californie, 23 mai 2022 (GLOBE NEWSWIRE) — Crocus Technology Inc., le premier fournisseur de capteurs XtremeSense® TMR (magnétorésistance à effet tunnel) ultramodernes, a annoncé aujourd’hui l’introduction de la famille de capteurs de courant isolés sans contact CT45x pour permettre des mesures de haute précision et de courant élevé à l’aide d’une solution simplifiée. Contrairement aux solutions existantes, le CT45x permet aux fabricants de se passer des coûteux blindages, concentrateurs et noyaux. Les CT452 et CT453 offrent une précision sans contact de 0,7 %, une bande passante de 1 MHz, et une immunité meilleure que -50 dB aux champs magnétiques externes sans composants mécaniques supplémentaires. Cette combinaison de performance et de précision permet aux clients de réduire la taille et le poids globaux de leur produit, ce qui leur permet de remplacer des modules de détection de courant coûteux et de grande taille par une solution simple et de faible encombrement.

Les exigences en termes de courants continuent de croître, s’accompagnant de difficultés pour mesurer précisément les courants élevés, généralement supérieurs à 200 A et allant souvent jusqu’à 2 000 A. Les résistances shunt avec amplificateurs isolés sont largement utilisées, mais elles posent un problème de pertes I²R et sont souvent de grandes dimensions et coûteuses. Les solutions existantes basées sur des effets magnétiques tels que l’effet Hall et les AMR (magnétorésistances anisotropes) sont moins précises et présentent une dérive à haute température. Les produits CT45x sont basés sur la technologie TMR XtremeSense, qui constitue l’avenir avec une approche sans contact à rapport signal/bruit (SNR) élevé capable d’évoluer avec les exigences du système, une bande passante élevée et un temps de réponse rapide, une réjection des champs de mode commun, combinés à des mesures de haute précision sur la température.

En outre, de nombreuses applications nécessitent désormais des mesures de courant très précises, de la gamme des milliampères jusqu’à celle des 1 000 A, voire plus. Souvent, ce type de solution nécessite plusieurs capteurs de courant pour obtenir les performances système souhaitées, et s’accompagne de nombreux compromis sur le design et complexités. L’utilisation des capteurs de courant TMR XtremeSense de Crocus permet de mettre en place une solution simple et sans compromis, grâce à un seul capteur CT45x qui fournit une large plage dynamique et un SNR (rapport signal/bruit) élevé. Par exemple, le CT45x est capable de mesurer jusqu’à 500 mA de résolution et jusqu’à 1 800 A tout en maintenant une précision supérieure à 0,7 %.

Le CT45x offre des performances révolutionnaires en matière de bruit, jusqu’à la valeur très basse de 0,55 mV_RMS, pour permettre aux applications de détecter de faibles niveaux de courant et de petits changements ou variations de courant via une barre omnibus. Cette performance est presque 10 fois supérieure à celle des solutions à effet Hall existantes. Il en résulte un rapport signal/bruit (SNR) pouvant atteindre 77 dB pour la mesure à l’aide des CT45x, ce qui permet au système de traiter des données à plus haute résolution avec une plus grande précision.

« Avec l’introduction de la famille CT45x de produits de détection de courant sans contact, nous disposons désormais d’un portefeuille complet de produits pour nos clients, des faibles courants aux courants beaucoup plus importants », a déclaré Zack Deiri, président-directeur général de Crocus Technology. « Ce produit basé sur la technologie de pointe TMR de Crocus est extrêmement enthousiasmant pour nous. En effet, les avantages de notre TMR XtremeSense permettent de répondre aux besoins des applications à courants plus élevés, alors que les solutions existantes ne peuvent y apporter de réponse sans compromis. Crocus se réjouit de s’adresser à de nouveaux marchés à courant élevé tels que ceux des BMS (systèmes de gestion de batterie), des onduleurs, des convertisseurs CC/CC et de bien d’autres dispositifs. »

Caractéristiques et performances des produits :

CT450 et CT452 (version 5 V) et CT453 (version 3,3 V)

Capteur de courant isolé sans contact

Capable de mesurer des courants de 5 mA à plus de 2 000 A

Erreur de sortie totale ±0,7 % à pleine échelle

Temps de réponse 300 ns, bande passante 1 MHz

Disponible dans six gammes différentes de champs configurés

Capacité de protection avec détection des champs excessifs (OFD)

Réjection des champs en mode commun (CMFR) intégrée avec plus de 90 % d’immunité (CT452/3)

Détection de champ magnétique uniforme (CT450)
Les applications ciblées se situent dans les domaines des chargeurs pour VE, des systèmes de gestion de batterie (BMS), des convertisseurs CC/CC, des systèmes 48 V, de la charge bidirectionnelle et des onduleurs CA/CC.

Le CT450 est disponible en conditionnement TSSOP-8. Les CT452/3 sont disponibles en conditionnement TSSOP-16 Pour de plus amples informations, veuillez consulter la page Web du produit :

CT450 https://crocus-technology.com/products/ct450/

CT452 https://crocus-technology.com/products/ct452/

CT453 https://crocus-technology.com/products/ct453/

À propos de Crocus Technology

Crocus Technology développe et fabrique des capteurs magnétiques de pointe basés sur sa technologie brevetée de capteurs TMR XtremeSense®. La technologie révolutionnaire de capteur magnétique de Crocus permet d’obtenir la sensibilité la plus élevée, la consommation d’énergie la plus faible et le plus faible encombrement sur une large gamme de températures. Le siège social de Crocus se trouve à Milpitas, en Californie. Pour tout complément d’information, veuillez consulter le site http://www.crocus-technology.com.

Pour tout complément d’information, veuillez contacter :

Crocus Technology
E-mail : info@crocus-technology.com

O CT45x apresenta as vantagens dos sensores TMR para repensar e simplificar as soluções no espaço das aplicações de alta precisão e alta corrente

MILPITAS, Califórnia, May 23, 2022 (GLOBE NEWSWIRE) — A Crocus Technology Inc., principal fornecedora de sensores disruptivos XtremeSense ® TMR (Tunnel Magneto-Resistance), anunciou hoje lançamento da família CT45x de sensores de corrente isolada sem contato para medições de alta precisão e alta corrente em uma solução mais simplificada. Ao contrário das soluções existentes, o CT45x permite que os fabricantes eliminem blindagens, concentradores ou núcleos caros. O CT452 e o CT453 oferecem precisão de 0,7% sem contato, largura de banda de 1 MHz e imunidade superior a -50 dB para campos magnéticos externos sem componentes mecânicos adicionais. Essa combinação de desempenho e precisão permite que os clientes reduzam o tamanho e o peso geral do produto, viabilizando a substituição dos módulos sensoriais atuais grandes e caros por uma solução pequena e simples.

O aumento dos requisitos atuais também aumentou os desafios das medições de altas correntes com precisão, tipicamente >200 A e muitas vezes até 2.000 A. Os resistores de derivação com amplificadores isolados são amplamente usados, mas apresentam um problema com perdas de I²R e tendem a ser grandes e caros. As soluções existentes de base magnética, tais como Hall Effect e AMR, são menos precisas e têm deriva de alta temperatura. Os produtos CT45x tem por vase a tecnologia XtremeSense TMR que oferece o futuro com uma abordagem sem contato de alta relação sinal-ruído (SNR) que pode ser dimensionada com os requisitos do sistema, alta largura de banda e tempo de resposta rápido, rejeição de campo de modelo comum, juntamente com as medições de alta precisão em condições de alta temperatura.

Além disso, muitas aplicações agora exigem medições de corrente muito precisas na faixa de até 1.000 A miliamperes ou mais. Muitas vezes, esse tipo de solução envolve vários sensores de corrente para alcançar o desempenho desejado do sistema com muitos comprometimentos e complexidades do projeto. O uso dos sensores de corrente XtremeSense TMR da Crocus viabiliza uma solução simples e sem comprometimento, por meio do uso de um único sensor CT45x que fornece uma grande faixa dinâmica e uma alta SNR. Por exemplo, o CT45x pode medir até 500 mA de resolução e até 1.800 A, mantendo uma precisão superior a 0,7%.

O CT45x oferece desempenho de ruído inovador, de até 0,55 mV_RMS, para permitir que as aplicações detectem pequenos níveis de corrente e pequenas mudanças ou variações de corrente através de um barramento. Este desempenho é quase 10 vezes melhor do que as soluções Hall Effect existentes. Isso resulta em uma SNR (relação sinal-ruído) de até 77 dB para a medição CT45x, o que permite que o sistema processe dados de maior resolução com maior precisão.

“Com a família CT45x de produtos de sensores atuais sem contato, passamos a oferecer um portfólio completo de produtos para os nossos clientes, desde pequenas correntes até correntes maiores”, disse Zack Deiri, Presidente e CEO da Crocus Technology. “Este produto que tem por base a tecnologia TMR de ponta da Crocus é o mais importante no momento, pois os benefícios do nosso XtremeSense TMR agora abordam as necessidades das aplicações atuais mais altas que não podem ser atendidas com soluções existentes sem comprometimento. A Crocus está entusiasmada em poder abordar novos mercados de alta corrente, como BMS, Inversores, DC/DC Converter e muitos outros.”

Características e desempenho do produto:

CT450 e CT452 (Versão 5 V) e CT453 (Versão 3.3 V)

Sensor de Corrente Isolado Sem Contato

Medição de correntes de 5 mA a >2.000 A

Total de erro da saída ±0,7% Completa e

Tempo de resposta de 300 ns, largura de banda de 1 MHz

Disponível em seis diferentes faixas de campo configuradas

Capacidade de proteção com Detecção de Excesso em Campo (OFD)

Rejeição de Campo de Modo Comum Integrado (CMFR) com > 90% de imunidade(CT452/3)

Detecção uniforme do campo magnético (CT450)
Foco em aplicações de direcionamento em Carregadores EV, Sistemas de Gerenciamento de Baterias (BMS), Conversores CC/CC, Sistema 48-V, Carregamento Bidirecional e Inversores CA/CC.

O CT450 está disponível em um pacote TSSOP-8. O CT452/3 está disponível no pacote TSSOP-16. Para mais informação, visite a página do produto em:

CT450 https://crocus-technology.com/products/ct450/

CT452 https://crocus-technology.com/products/ct452/

CT453 https://crocus-technology.com/products/ct453/

Sobre a Crocus Technology

A Crocus Technology desenvolve e fabrica sensores magnéticos de última geração com base na sua tecnologia patenteada de sensores XtremeSense® TMR. A tecnologia do sensor magnético disruptivo da Crocus viabiliza a mais alta sensibilidade, o menor consumo de energia e o menor tamanho em uma ampla faixa de temperatura. A sede da Crocus está localizada em Milpitas, Califórnia. Para mais informação, visite http://www.crocus-technology.com.

Para mais informações, contate:

Crocus Technology
Email: info@crocus-technology.com